Week three of the college football season was the craziest yet as four teams in the top 25 lost last Saturday. If you missed any of those upsets, here's a quick recap:

  • #24 South Carolina knocked off #6 Georgia in Columbia.
  • Boston College shocked #9 USC.
  • #17 Virginia Tech made a comeback effort, but came up short against East Carolina.
  • Virginia came out on top over #21 Louisville in a game that came down to the wire.

As the season progresses, you will begin to see more and more big-time favorites losing games. This week, we could have a huge shake up in the top 10 if just one of the teams we put on upset alert loses.

Here are the teams that need to be cautious of their opponent this week:

 

  • #22 Clemson at #1 Florida State

    Line: Florida State -17

    Florida State school officials announced earlier this week that Jameis Winston would be suspended for the first half of this weekend's game against Clemson. One half without your starting quarterback can make a huge difference. The Seminoles will to have to rely on sophomore quarterback Sean Maguire to survive the first half. Maguire's only game experience was against the Citadel where he went 3-5 for 28 yards. Running back Karlos Williams will need to have a big day on the ground to help FSU score without Winston.

    Clemson was favored, by some, to beat Florida State last season. That plan didn't turn out so well, and that team's best players left for the NFL. This game will also be played away from Death Valley, which makes it an even bigger challenge. Quarterback Cole Stoudt will need a big game through the air and get some points on the board early. The defense, led be Vic Beasley, will need to put pressure on Maguire and try to force him into mistakes.

    The Tigers were very capable of beating FSU with or without Winston, but those chances have improved with the suspension of Heisman winner. Florida State is more talented overall, but we will find out on Saturday if that will be enough.

    (Photo by Streeter Lecka/Getty Images)
    (Photo by Streeter Lecka/Getty Images)
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  • Florida at #3 Alabama

    Line: Alabama -15

    Alabama has finally established that Blake Sims will be the starting quarterback. The concern now shifts to the secondary. In week one, Alabama gave up 365 passing yards to West Virginia. Now they open up conference play with defensive backs Eddie Williams and Jarrick Williams injured, while safety Nick Perry will be suspended for the first half because of a targeting penalty last week. Florida will try to throw the ball and take advantage of the Tide's thin secondary.

    Florida would be a more popular pick if the team didn't squeak out a three-overtime win against Kentucky last Saturday. The argument can be made that the Wildcats have drastically improved or you can just say the Gators were looking ahead to this game. Whatever the case, they still have a chance of beating Alabama. Florida has a talented secondary, which will be needed to a receiving core led by Amari Cooper. Expect Jeff Driskel to throw the ball a lot against this defense. Will Muschamp will need to come up with a creative game plan to be able to jump out in front of the Tide.

    Alabama has not lost in Bryant-Denny Stadium since 2012 when Texas A&M shocked the Crimson Tide. It may be hard to see that happening this Saturday with the way the Gators played against Kentucky, but Florida has enough talent to match up. Will it be enough?

    (Photo by Kevin Cox/Getty Images)
    (Photo by Kevin Cox/Getty Images)
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  • #4 Oklahoma at West Virginia

    Line: Oklahoma -8

    Last week, we put Oklahoma on upset alert against Tennessee. The Volunteers played hard, but they didn't have enough juice. So why are the Sooners on upset alert again this week? Because West Virginia has the most explosive offense they have faced all year. The Sooners are playing without running back Keith Ford so Trevor Knight will carry more of the workload.

    Oklahoma has a good chance of slowing down West Virginia, but that does not mean they will do it. Quarterback Clint Trickett leads the BIG 12 in passing yards and has thrown seven touchdowns to just one interception. Expect Dana Holgorsen to come at the Sooners fast similar to what he did to Alabama in week one. Holgorsen will need to scheme his offense to score a lot of points, but if he truly wants to pull the upset, he will need to overhaul his defense. If the Mountaineers can figure out a way to slow down Knight and the rest of the Sooner offense, then it will be a close ballgame.

    (Photo by Brett Deering/Getty Images)
    (Photo by Brett Deering/Getty Images)
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  • #5 Auburn at #20 Kansas State

    Line: Auburn -9

    Last season, Auburn was on the winning end of a handful of upsets. This year, Malzahn hopes to avoid the flip side, but beating Auburn will not be easy. The Tigers have one of the best offenses in the country behind dual-threat quarterback Nick Marshall. The unique style of spread they run keeps defenses constantly confused. The real concern for this game will be how the defense handles Kansas State. The Tigers do have playmakers, but they will be without defensive back Jermaine Whitehead on Thursday night. One player's absence can make a huge difference against Kansas State quarterback Jake Waters.

    The Wildcats may not be able to slow down Auburn's offense, but they can outscore them. That is mostly because of Waters. He currently leads the BIG 12 in rushing. Yes, you read that correctly. A quarterback leads the BIG 12 in rushing yards. Even when he is not running the ball, he has a great wide receiver in Tyler Lockett to throw to. A solid defensive performance is vital for KSU, but moving the ball down the field will be the ultimate factor.

    Both teams had a bye week prior to this game, so expect to see some creativity. Kansas State fans are going to be loud because they know what an upset would do for the program. It may be hard to imagine Auburn losing, but just remember that Bill Snyder has pulled 13 upsets in the last five years.

     

    (Photo by Mike Zarrilli/Getty Images)
    (Photo by Mike Zarrilli/Getty Images)
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  • Mississippi State at #8 LSU

    Line: LSU -10

    Early in the season, LSU's inexperience has shown, but the potential of this football team was seen in a fourth quarter comeback against Wisconsin. Quarterback Anthony Jennings continues to improve along with that offense, but there's no denying that the Tigers' defense is the backbone to its success. And that defense will have its hands full this weekend against Mississippi State quarterback Dak Prescott. LSU cannot put the game in the hands of itsoffense so it's vital that Les Miles and John Chavis figure out a way to stop Prescott.

    But Dak Prescott is not the only big time player in a maroon uniform. Defensive lineman Preston Smith became the first player in conference history to win three consecutive SEC defensive lineman of the week awards. He will need to be a leader in shutting down LSU's run game on Saturday.

    The Bulldogs are averaging over 43 points per game, their highest total through three games since 1944. Winning in a loud Tiger Stadium is no easy task for anyone, but Mississippi State has enough talent to do it.

    LSU has been one of the most consistent teams in college football, but the program has suffered a few upsets in recent years. Last year, Ole Miss knocked off the Tigers. Can the other Magnolia State school do it this year?

     

    (Photo by Stacy Revere/Getty Images)
    (Photo by Stacy Revere/Getty Images)
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